By B.G.J. Knols, C. Louis
Modern examine on genetic keep watch over of disease-transmitting bugs understands forms of scientists: those who paintings within the laboratory and people referred to as ‘field people’. during the last decade, either teams appear to have constructed differing learn priorities, handle essentially diversified points in the total self-discipline of infectious-disease keep watch over, and worse, have constructed a systematic ‘language’ that's now not understood by means of the ‘other’ social gathering. This hole widens each day, among the North and the South, among ecologists and molecular biologists, geneticists and behaviourists, and so forth. the necessity to improve a standard examine schedule that bridges this hole has been pointed out as a best precedence by means of all events concerned. basically then shall the objective of constructing acceptable genetic-control innovations for vectors of ailment turn into fact. This ebook is the mirrored image of a workshop, held in Nairobi (Kenya) in July 2004. It introduced jointly a superb illustration of either molecular and ecological examine and, for the 1st time, integrated an important variety of researchers from disease-endemic international locations.
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Additional resources for Bridging Laboratory and Field Research for Genetic Control of Disease Vectors (Wageningen UR Frontis Series)
There is, however, no coordination of these activities (see section 6). g. ) have addressed many analogous problems related to present-day site selection and characterization, albeit without the genetic-engineering component that adds new and unique concerns. The following sections focus on GM mosquitoes, though most concepts apply similarly to other disease vectors. Issues and challenges The transition of laboratory research on GM mosquitoes to full programmatic implementation in disease-endemic settings encompasses a series of steps, each with its own unique challenges.
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Issues and challenges An important issue in addressing pathogen evolution relates to consensus building of exactly what is meant when one refers to resistance and virulence. Definition of these terms will avoid confusion and aid in the development of unified conclusions across different research groups studying those topics. It will be critical to develop non-onerous means for assessing the capacity for parasites to avoid interference from GMVs and to characterize virulence of resistant parasites.