By Alan B. Weder (auth.), Norman K. Hollenberg MD, PhD (eds.)
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Extra info for Atlas of Heart Diseases: Hypertension: Mechanisms and Therapy
In this study of normotensive men, lowering the potassium intake from a usual level (90 mEq/ d) to a very low level (10 mEq/ d) induced an increase in blood pressure and a decrease in plasma potassium concentration . The mechanisms that mediate the effect of potassium restriction on blood pressure are not known but may include sodium retention, hormonal changes, and inhibition of membrane Na+ -K+ ATPase. (Adapted from Krishna et al. 5 70 ~- <1),01 FIGURE 1-49. Dietary sodium intake may interact with other social and cultural factors to impact blood pressure.
Am J Clin Nutr 1988, 48:1463-1470. 59. Criqui MH, Langer RD, Reed DM: Dietary alcohol, calcium, and potassium: independent and combined effects on blood pressure. Circulation 1989, 80:609-614. 60. Green LW: Manual for scoring socioeconomic status for research on health behavior. Public Health Rep 1970, 85:815-827. 61. : The association of skin color with blood pressure in US blacks with low socioeconomic status. JAMA 1991,265:599-602. 62. Simopoulos AP: Dietary risk factors for hypertension. Comp Ther 1992,18:26-30.
Sixty obese and 18 nonobese adolescents were tested for the effects of successive 2-week periods of high (> 250 mEq/ d) and low « 30 mEq/ d) dietary salt intake on blood pressure (BP), cardiac output (CO), and plasma volume (PV). A, Compared with nonobese adolescents, obese individuals showed greater changes in BP (salt sensitivity), CO, and PV. B, Obese adolescents were then offered a 20-week weight-loss program. A total of 36 lost more than 1 kg of body weight (light bars), whereas 15 did not (dark bars).