By David G. Kleinbaum, Kevin M. Sullivan, Nancy D. Barker
This e-book includes the content material of the ActivEpi CD-ROM pages plus extra routines and an appendix on computing device programs.
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Extra info for ActivEpi Companion Textbook
5. 6. 7. 8. 9. 8 1. 2. 3 translates to a 130% increase in the risk of current smokers compared to never smokers. 3 translates to a 30% increase in the risk for previous smokers compared to never smokers. This page intentionally left blank 37 LESSON 3 EPIDEMIOLOGIC STUDY DESIGNS A key stage of epidemiologic research is the study design. This is defined to be the process of planning an empirical investigation to assess a conceptual hypothesis about the relationship between one or more exposures and a health outcome.
Ate at restaurant A? The health outcome variable, D, indicates whether or not a study subject was clinically diagnosed with Legionnaires Disease during the three week period from mid to late October. The exposure variable is conceptually whatever variable indicates the main source of the outbreak. Since this variable is essentially unknown at the start of the study, there is a large collection of exposure variables, all of which need to be identified as part of the study design and investigated as candidates for being the primary source of the outbreak.
Choices Preventive Therapeutic For each of the following features, choose the option that applies to clinical trials: 1. The investigator's role regarding exposure: a. assign b. observe . ???. 2. Subject selection into groups: self-selection . . b. randomization . 3. Directionality: . a. backwards . b. forwards . c. non-directional . 4. Timing: . . a. prospective . . b. retrospective . c. either ??? 5. Blinding: . a. single . . b. double . . c. either ??? 6. Topic: . a. medication . .